Epigenetic dysregulation of immune-related pathways in cancer: bioinformatics tools and visualization
نویسندگان
چکیده
منابع مشابه
Epigenetic alteration and microRNA dysregulation in cancer
MicroRNAs (miRNAs) play pivotal roles in numerous biological processes, and their dysregulation is a common feature of human cancer. Thanks to recent advances in the analysis of the cancer epigenome, we now know that epigenetic alterations, including aberrant DNA methylation and histone modifications, are major causes of miRNA dysregulation in cancer. Moreover, the list of miRNA genes silenced ...
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Medullary thyroid carcinoma (MTC) is an infrequent calcitonin-producing neuroendocrine tumor that initiates from the parafollicular C cells of the thyroid gland. Several genetic and epigenetic alterations are collaterally responsible for medullary thyroid carcinogenesis. In this review article, we shed light on all the genetic and epigenetic hallmarks of MTC. From the genetic perspective, RET, ...
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ژورنال
عنوان ژورنال: Experimental & Molecular Medicine
سال: 2021
ISSN: 1226-3613,2092-6413
DOI: 10.1038/s12276-021-00612-z